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Glutathione skin whitening

When talking about general skin whitening, there’s always one solution that most individuals can think of Glutathione Injections.

The role of glutathione as a skin-lightening agent was an accidental discovery when skin lightening was noticed as a side effect of large doses of glutathione.

Various mechanisms for the hypopigmentary effect of glutathione have been proposed, with inhibition of tyrosinase being the most important. Glutathione can reduce tyrosinase activity in three different ways. Tyrosinase is directly inhibited through chelation of the copper site by the thiol group. Secondly, glutathione interferes with the cellular transfer of tyrosinase to premelanosomes, a prerequisite for melanin synthesis. Thirdly, tyrosinase inhibition is effected indirectly via its antioxidant effect. Glutathione shifts melanogenesis from eumelanin to phaeomelanin synthesis by reactions between thiol groups and dopaquinone leading to the formation of sulfhydryl-dopa conjugates.

Glutathione has potent antioxidant properties. The free radical scavenging effect of glutathione blocks the induction of tyrosinase activity caused by peroxides. Glutathione has been shown to scavenge ultraviolet radiation induced reactive oxygen species generated in epidermal cells. A recent study on melasma patients noted significantly higher levels of glutathione-peroxidase enzyme in patients compared to controls, confirming the role of oxidative stress in melasma. Based on these observations, the potential of glutathione in management of melasma and hyperpigmentation seems plausible.

Treatments involve anywhere from 40mg/Kg of glutathione combined with vitamin C, administered once a week. 10 treatments could be necessary to see the desired results. IVs are administered by our highly experienced nurses. Even once the skin is lightened, patients have to come back every few months for maintenance. As the glutathione levels fade, so do the effects.

Here are a few possible side effects that may occur rarely while getting a skin whitening injections: Aggravate symptoms of asthma, Weight gain, losing pigmentation of hair, Nausea, Allergic reactions on skin, Diarrhea and stomach problem

If you would like to learn more about how you could benefit from this treatment, please book a consultation appointment.


Address : SKIN111 Clinic, Nakheel Mall - Palm Jumeirah (LG floor, next to Emirates Islamic Bank)
Tel : 04-5542846
054-3359444

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